Ulrich Bogdahn Selected Research

Transforming Growth Factor beta2

10/2014	Versican isoform V1 regulates proliferation and migration in high-grade gliomas.
1/2013	Lactate-modulated induction of THBS-1 activates transforming growth factor (TGF)-beta2 and migration of glioma cells in vitro.
12/2011	TGF-β2 signaling in high-grade gliomas.
11/2009	Treatment of malignant gliomas with TGF-beta2 antisense oligonucleotides.
8/2009	Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2.
4/2007	Toll-like receptor triggered dendritic cell maturation and IL-12 secretion are necessary to overcome T-cell inhibition by glioma-associated TGF-beta2.
1/2007	Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: from preclinical to phase I/II studies.
2/2006	Targeted tumor therapy with the TGF-beta 2 antisense compound AP 12009.

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Ulrich Bogdahn Research Topics

Disease

34	Glioma (Gliomas) 01/2019 - 09/2002
26	Neoplasms (Cancer) 01/2019 - 03/2002
15	Glioblastoma (Glioblastoma Multiforme) 03/2016 - 12/2003
11	Stroke (Strokes) 01/2015 - 01/2005
7	Brain Neoplasms (Brain Tumor) 01/2017 - 03/2002
6	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 01/2012
5	Neoplasm Metastasis (Metastasis) 10/2008 - 03/2002
4	Spinal Cord Injuries (Spinal Cord Injury) 01/2021 - 07/2006
4	Ischemic Stroke 05/2012 - 03/2005
4	Melanoma (Melanoma, Malignant) 01/2005 - 03/2002
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 06/2007
3	Disease Progression 01/2021 - 06/2006
3	Ischemia 04/2013 - 09/2006
3	Huntington Disease (Huntington's Disease) 01/2011 - 06/2007
2	Medulloblastoma 01/2018 - 01/2008
2	Meningioma (Meningiomas) 01/2017 - 01/2017
2	Hypertension (High Blood Pressure) 01/2017 - 03/2016
2	Parkinson Disease (Parkinson's Disease) 01/2017 - 06/2008
2	Neuroinflammatory Diseases 10/2015 - 04/2010
2	Edema (Dropsy) 04/2013 - 11/2009
2	Multiple Sclerosis 06/2010 - 04/2010
2	Coma (Comas) 01/2009 - 04/2007
2	Pathologic Constriction (Stenosis) 06/2003 - 01/2002
1	Neutropenia 01/2021
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 03/2020
1	Pathologic Processes 03/2020
1	Cerebral Cortical Thinning 01/2018
1	Quadriplegia (Spastic Quadriplegia) 01/2017
1	Respiratory Insufficiency (Respiratory Failure) 01/2017
1	Myocardial Infarction 01/2017
1	Heart Arrest (Cardiac Arrest) 01/2017
1	Clinical Deterioration 01/2017
1	Myelitis 01/2017
1	Cardiac Arrhythmias (Arrythmia) 04/2016
1	Heart Failure 04/2016

Drug/Important Bio-Agent (IBA)

10	Transforming Growth Factor beta (TGF-beta)IBA 10/2014 - 02/2006
10	Proteins (Proteins, Gene)FDA Link 01/2013 - 03/2002
8	Pharmaceutical PreparationsIBA 01/2021 - 04/2007
8	Transforming Growth Factor beta2IBA 10/2014 - 02/2006
8	Temozolomide (Temodar)FDA LinkGeneric 09/2011 - 03/2005
6	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2021 - 01/2011
5	Metformin (Glucophage)FDA LinkGeneric 01/2019 - 01/2016
5	TrabedersenIBA 12/2011 - 01/2005
5	liposomal doxorubicin (Doxil)FDA Link 09/2009 - 09/2002
4	Antisense OligonucleotidesIBA 01/2022 - 01/2005
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2004
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2016 - 07/2007
4	Lactic Acid (Lactate)FDA LinkGeneric 01/2015 - 08/2009
3	CytokinesIBA 01/2021 - 04/2007
3	Hypoglycemic Agents (Hypoglycemics)IBA 01/2019 - 03/2016
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 01/2016
3	Small Interfering RNA (siRNA)IBA 10/2014 - 06/2006
3	Peptides (Polypeptides)IBA 04/2013 - 09/2002
3	Lactate Dehydrogenase 5IBA 02/2013 - 08/2009
3	Messenger RNA (mRNA)IBA 11/2009 - 03/2002
3	Biological ProductsIBA 07/2008 - 09/2002
2	Insulin (Novolin)FDA Link 01/2017 - 03/2016
2	SteroidsIBA 01/2017 - 01/2009
2	ORALIT (ORS)IBA 01/2017 - 01/2016
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2016 - 01/2015
2	Sunitinib (Sutent)FDA Link 01/2016 - 01/2014
2	Tyrosine Kinase InhibitorsIBA 01/2016 - 01/2014
2	Diclofenac (SR 38)FDA LinkGeneric 01/2015 - 02/2013
2	Protein Isoforms (Isoforms)IBA 10/2014 - 12/2011
2	Contrast MediaIBA 02/2014 - 01/2012
2	Interleukin-12 (IL 12)IBA 02/2013 - 04/2007
2	Toll-Like Receptors (Toll-Like Receptor)IBA 02/2013 - 04/2007
2	Transcription Factors (Transcription Factor)IBA 01/2012 - 04/2010
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 09/2011 - 09/2002
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 07/2010 - 03/2006
2	AntigensIBA 07/2007 - 03/2002
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2007 - 03/2004
1	Transforming Growth Factor-beta Type II ReceptorIBA 01/2022
1	Filgrastim (Neupogen)FDA Link 01/2021
1	statticIBA 01/2017
1	CalciumIBA 01/2017
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2017
1	Triglycerides (Triacylglycerol)IBA 01/2017
1	NitratesIBA 01/2017
1	DiureticsIBA 01/2017
1	HDL LipoproteinsIBA 01/2017
1	Complement System Proteins (Complement)IBA 01/2017
1	eculizumab FDA Link 01/2017
1	Estrogens (Estrogen)FDA Link 01/2017
1	Immunoglobulins (Immunoglobulin)IBA 01/2017
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2017
1	Cardiac GlycosidesIBA 04/2016

Therapy/Procedure

22	Therapeutics 01/2017 - 09/2002
9	Drug Therapy (Chemotherapy) 01/2021 - 02/2004
3	Radiotherapy 09/2009 - 12/2003
2	Chemoradiotherapy 01/2018 - 08/2005
2	Aftercare (After-Treatment) 01/2017 - 01/2008
2	Glycemic Control 01/2017 - 03/2016
2	Salvage Therapy 07/2010 - 12/2003
2	Sutures (Suture) 09/2006 - 10/2005
1	Hematopoietic Stem Cell Mobilization 01/2019
1	Combination Drug Therapy (Combination Chemotherapy) 01/2018
1	Deep Brain Stimulation 01/2017
1	Plasmapheresis 01/2017